Similar findings came in a separate study of Australian smokers by Michele Pergadia, Ph.D., and colleagues.
Both sets of researchers suggest that the genomic region labeled 3p26-3p25 may be an important area for further genetic research on depression.
“The significance of this finding remains uncertain, although it points to a gene that might hold significant promise for further developments in studying the pathophysiology and treatment of major depressive disorder,” wrote Steven Hamilton, M.D., Ph.D., of the Department of Psychiatry and Institute for Human Genetics at the University of California, San Francisco, in a commentary in the August American Journal of Psychiatry.
Abstracts of the two studies and the commentary can be read at:
Breen: http://ajp.psychiatryonline.org/cgi/content/abstract/168/8/840.Hamilton: http://ajp.psychiatryonline.org/cgi/content/abstract/168/8/783.