Now, researchers based at the Scripps Research Institute in La Jolla, Calif., have produced a high-resolution three-dimensional image of JDTic bound to the human KOR. The emerging picture reveals critical new information that helps explain why JDTic binds so tightly and specifically to this particular opioid receptor. Their findings were published online March 21 in Nature.
“Drug abuse and addiction remain devastating public health challenges in the United States,” “This research could aid in the development of effective medications for the treatment of drug addiction, particularly to stimulants like cocaine," said NIDA Director Nora Volkow, M.D.
To read about another medication that shows promise for treating opioid addiction, see Psychiatric News here.
(Image: Yekaterina Kadyshevskaya, The Scripps Research Institute)