The first clue to the mutation came about when researchers at the Icelandic company DeCode Genetics scanned the entire DNA of 1,795 Icelanders. About 1 in 100 had a mutation in the gene for a large protein that is sliced to form beta amyloid. Then the investigators studied people who had been given an Alzheimer’s diagnosis and a group of people aged 85 and older. Those with the mutation appeared to be protected from Alzheimer’s disease.
Read more about the quest to find effective treatments for Alzheimer's disease in Psychiatric News, here.