How inflammation and depression interact is not well understood, wrote Børge Grønne Nordestgaard, M.D., D.M.Sc., of the Herlev Hospital, Copenhagen University Hospital in Denmark, but inflammation may cause depression by reducing levels of serotonin, or depression may cause inflammation by activating stress hormones.
“More research is needed to establish the direction of the association between CRP and depression,” said the researchers. In addition, intervention studies might test whether adding anti-inflammatory drugs to antidepressant treatment of depression would affect outcomes, they suggested.
To read more about recent research on the association between inflammation and psychiatric disorders, see Psychiatric News here and here.
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